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Matrixyl 3000 + Argireline

30 ml / 1 fl oz · Fragrance-free

Two peptide systems aimed squarely at expression lines. Matrixyl works on the support structure underneath; Argireline works on the surface tension lines that repeat movement leaves behind.

$24

About 3–4 weeks of daily use — roughly $0.86 a day.

Pairs with the GHK-Cu Duo — $49
  • Free US shipping over $50, ships in 1–2 business days
  • 60-day empty-bottle guarantee — nothing to send back
  • Layers with copper peptides without pilling
  • Fragrance-free, vegan, cruelty-free, made in the USA
Key active
Matrixyl 3000 (palmitoyl tripeptide-1 and tetrapeptide-7), Argireline (acetyl hexapeptide-8)
Supporting
Sodium hyaluronate, glycerin
Texture
Clear, lightweight fluid
Best for
Expression lines, forehead, crow's feet
When
AM and PM
Skin types
All, including sensitive

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Why It Goes With Copper Peptides

What this adds to the GHK-Cu routine.

Every product here has to earn a place next to the peptide. Here is the specific reason this one does.

The pairing

Matrixyl 3000 + Argireline + GHK-Cu

Copper peptides and Matrixyl are different families doing different jobs, which is exactly why they stack well. GHK-Cu is a signalling peptide concerned with repair and firmness; Matrixyl 3000 is a matrix-support peptide concerned with the appearance of established lines. Neither is an acid or a retinoid, so combining them adds no irritation load at all.

  • Order: Copper Peptide Serum first, this second, cream last. Or alternate - copper AM, peptides PM.
  • Interaction risk: None — no acids, no retinoids, no fragrance in either product
  • Best judged at: 8–12 weeks, same light, same spot
Shop the GHK-Cu Duo →
SkincareLabs copper peptide serum and booster cream

What It Does

Where it earns its place.

What to expect, and roughly when. Surface changes read first; structural ones take longer.

EXPRESSION

Where movement leaves marks

Forehead, between the brows, the outer corners of the eyes. The lines that started as expressions and stayed put.

STACKING

No irritation cost

Peptides do not exfoliate, sensitise or thin the barrier, so adding a second peptide serum does not add risk the way a second acid would.

TIMELINE

Eight to twelve weeks

Peptide results are cumulative and quiet. If you want a fair read, photograph the same spot in the same light on week one and week twelve.

Ingredients (INCI)

Water (Aqua), MATRIXYL 3000 (Glycerin, Water, Butylene Glycol, Carbomer, Polysorbate 20, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7), ARGIRELINE peptide (Water, Potassium Sorbate, Acetyl Hexapeptide-8, Phenoxyethanol), Vegan Hyaluronic Acid (Sodium Hyaluronate), Contains less than 2% of Phenoxyethanol, Benzoic Acid, Dehydroacetic Acid.

How to Use

Where it sits in the routine.

01

When

AM and PM.

02

Order

Copper Peptide Serum first, this second, cream last. Or alternate - copper AM, peptides PM.

03

Seal it in

Finish with a moisturiser, and SPF over the top in the morning. An unsealed water-based step evaporates.

Layering with the rest of the range: full layering guide →

The Formula

Short list, on purpose.

What's in it

  • Matrixyl 3000 (palmitoyl tripeptide-1 and tetrapeptide-7), Argireline (acetyl hexapeptide-8)The active this product is built around.
  • Sodium hyaluronate, glycerinSupporting cast — comfort, slip and hydration.

What's not

  • Fragrance & essential oilsNothing to react to.
  • Alcohol denat.No short-term tightening trick.
  • DyesColour comes from the formula or not at all.
Reviews section intentionally omitted: the store is live and a review block with nothing real in it is either empty or invented. It returns when a review app has genuine verified orders behind it.

Questions

About matrixyl 3000 + argireline.

How does matrixyl 3000 + argireline fit with copper peptides?

Copper peptides and Matrixyl are different families doing different jobs, which is exactly why they stack well. GHK-Cu is a signalling peptide concerned with repair and firmness; Matrixyl 3000 is a matrix-support peptide concerned with the appearance of established lines. Neither is an acid or a retinoid, so combining them adds no irritation load at all.

When should I use it?

AM and PM. Copper Peptide Serum first, this second, cream last. Or alternate - copper AM, peptides PM.

Is it fragrance-free?

Yes. Nothing in the SkincareLabs range carries added fragrance or essential oils, so there is nothing in it to react to.

Will it pill under makeup?

It shouldn't — there are no silicones or film-formers in it. If you get pilling, it's almost always a product further up the stack, or not waiting thirty seconds before the next layer.

Is it pregnancy-friendly?

There's no retinoid, no salicylic acid and no fragrance in it. That said, we're a skincare brand, not your clinician — run it past your OB or midwife first.

Better together

Built around the peptide.

Matrixyl 3000 + Argireline is designed to sit alongside GHK-Cu, not compete with it. The Duo is both copper peptide steps, priced as one.

Shop the Duo — $49